Hydroxypropyl methyl selulose HPMC ni selile ya ionic selulose ivanze ether muburyo butandukanye na ionic methyl carboxymethyl selulose ivanze ether, ntabwo ikora hamwe nibyuma biremereye.Umwuka umwe wa ogisijeni kubera hydroxypropyl methyl selulose hamwe nuburinganire butandukanye bwibintu bya hydroxypropyl hamwe nubukonje, byahindutse ubwoko butandukanye kumikorere, kurugero, ibinyabuzima byinshi bya vitamine hamwe nibirimo bike bya hydroxypropyl, imikorere yayo yegereye methyl selile na methoxyl nkeya ibirimo nibirimo byinshi byubwoko bwa hydroxypropyl, kandi nibikorwa byegeranye na hydroxypropyl methyl selulose ikorwa.Ariko muri buri bwoko, nubwo burimo gusa hydroxypropyl nkeya cyangwa methoxy nkeya, solubile mumashanyarazi cyangwa ubushyuhe bwa flocculation mubisubizo byamazi, hariho itandukaniro rinini.
1, hydroxypropyl methyl selulose solubility
Hydroxypropyl methyl selulose mu gukemura amazi ya hydroxypropyl methyl selulose mubyukuri ni ubwoko bwa oxyde ya propylene (impeta ya methyl oxypropyl impeta) yahinduwe na methyl selulose, bityo iracyafite ibisa na methyl selulose amazi akonje kandi ashushe amazi adashonga.Nyamara, ubushyuhe bwa gelation ya hydroxy propyl yahinduwe irarenze cyane irya methyl selulose mumazi ashyushye.Kurugero, viscosity ya hydroxypropyl methylcellulose yumuti wamazi hamwe na 2% yibikorwa bya DS = 0,73 nibirimo hydroxypropyl MS = 0.46 ni 500 mpa kuri 20 ℃.Ubushyuhe bwa gel bwibicuruzwa bya S bigera kuri 100 ℃, mugihe methyl selulose yubushyuhe bumwe ari 55 only gusa.Kubijyanye no gukomera kwayo mumazi, nayo yarateye imbere cyane, kurugero, nyuma yo kumenagura hydroxypropyl methylcellulose (imiterere yintete 0.2 ~ 0.5mm kuri 20 ℃ 4% yibicu byamazi yibicuruzwa 2pA? S birashobora gushonga byoroshye mumazi bidakonje mubushyuhe bwicyumba .
. DS = 0.2 ~ 1.Irashobora kandi gushonga muri hydrocarbone ya chlorine nka dichloromethane na trichloromethane, hamwe na solge organic nka acetone, alcool isopropyl, na alcool ya diacetone.Gukemura kwayo mumashanyarazi kama biruta gukomera kwamazi.
2, hydroxypropyl methyl selulose viscosity yibintu bigira ingaruka
Hydroxypropyl methylcellulose yibintu bya hydroxypropyl methylcellulose igena ubukonje busanzwe, hamwe na selile yandi ya selile ni imwe, iri kuri 20 ℃ hamwe nigisubizo cyamazi cya 2% nkicyemezo gisanzwe.Ubukonje bwibicuruzwa bimwe, hamwe no kwiyongera kwibitekerezo no kwiyongera, guhuriza hamwe kwibicuruzwa bitandukanye bya molekuline, uburemere bwa molekuline yibicuruzwa ni viscosity nyinshi.Isano yayo nubushyuhe isa nubwa methyl selulose.Iyo ubushyuhe buzamutse, ibishishwa bitangira kugabanuka, ariko iyo bigeze ku bushyuhe runaka, ubukonje burazamuka butunguranye kandi gelation ibaho.Ubushyuhe bwa gelation yibicuruzwa bifite ubukonje buke burenze ubw'ibicuruzwa bifite ubukonje bwinshi.Urwego rwa gel point yarwo, hiyongereyeho ubukonje bwinshi kandi buke bwa ether, ariko kandi hamwe na ether mikorerexy na hydroxypropyl matsinda yibigize hamwe nurwego rwose rwo gusimbuza bifitanye isano.Tugomba kumenya ko hydroxypropyl methylcellulose nayo ari pseudoplastique;igisubizo cyacyo gihamye iyo kibitswe mubushyuhe bwicyumba kandi ntigaragaza ko hari iyangirika ryubwiza usibye ko bishoboka kwangirika kwimisemburo.
3, hydroxypropyl methyl selulose aside hamwe no kurwanya alkaline
Hydroxypropyl methylcellulose aside alkali hydroxypropyl methylcellulose na alkali, muri rusange irahagaze neza, murwego rwa ph PH2 ~ 12 ntirugiraho ingaruka, irashobora kwihanganira urugero runaka rwa acide yumucyo, nka acide formique, acide acike, aside citricike, aside succinic, fosifori aside, aside boric, nibindi. Ariko aside yibanze ifite ingaruka zo kugabanya ububobere.Alkali nka soda ya caustic, potasiyumu ya caustic n'amazi ya lime nta ngaruka bigira kuri yo, ariko ingaruka zo kongera gato ubukonje bwumuti zizagabanuka buhoro buhoro mugihe kizaza.
4, hydroxypropyl methyl selulose irashobora kuvangwa
Hydroxypropyl methyl selulose yumuti irashobora kuvangwa namazi ya elegitoronike ya polymer, hanyuma igahinduka igisubizo kiboneye hamwe nubwiza bwinshi.Izi molekile nyinshi ni polyethylene glycol, polyvinyl acetate, polysilicone, polymethyl vinyl siloxane na hydroxyethyl selulose na methyl selulose, nibindi. igisubizo.Hydroxypropyl methyl selulose irashobora kandi kuvangwa na acide stearic cyangwa palmitic aside mannitol ester cyangwa sorbitol ester, ariko kandi hamwe na glycerol, sorbitol na mannitol, ibyo bikoresho bishobora gukoreshwa nka hydroxypropyl methyl selulose plastike.
5, hydroxypropyl methyl selulose amazi adashonga amazi
Hydroxypropyl methyl selulose idashobora gukama amazi-solubose ya selile, irashobora kuba hejuru-ihuza na aldehydes, kandi bigatuma ether-ere-e-e-e-e-e-e-e-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-e-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et-et)Kandi ukore hydroxypropyl methylcellulose idashobora gushonga aldehyde, formaldehyde, glyoxal, succinaldehyde, dialdehyde, nibindi, gukoresha fordehide bigomba kwitondera byumwihariko agaciro ka PH k'igisubizo, aho reaction ya glyoxal yihuta, bityo mubikorwa byinganda bikunze gukoreshwa glyoxal nkumusaraba -umukozi uhuza.Igipimo cyubwoko nkubu bwo guhuza ibisubizo ni 0.2% ~ 10% bya ether mass, ibyiza ni 7% ~ 10%, nko gukoresha glyoxal hamwe na 3.3% ~ 6% nibyo bikwiye.Ubushyuhe rusange bwo kuvura ni 0 ~ 30 ℃, igihe ni 1 ~ 120min.Igikorwa cyo guhuza ibikorwa kigomba gukorwa mugihe cya acide.Mubisanzwe, acide organic organique cyangwa acide karubasi ya acide yongewe kumuti kugirango uhindure PH yumuti kuri 2 ~ 6, byaba byiza hagati ya 4 ~ 6, hanyuma aldehydes ikongerwamo kugirango ihuze reaction.Acide ikoreshwa ni aside hydrochloric, aside sulfurike, aside fosifori, aside aside, aside acike, aside hydroxy acetike, acide succinic cyangwa acide citricike, muri yo harimo aside aside cyangwa aside irike nziza, naho aside irike ni nziza.Acide na aldehydes birashobora kandi kongerwaho icyarimwe kugirango yemere igisubizo guhuzwa murwego rwifuzwa rwa PH.Iyi reaction ikoreshwa kenshi muburyo bwa nyuma bwo gutegura selile ya selile, kugirango ether ya selile idashonga, byoroshye gukoresha 20 ~ 25 ℃ amazi yo gukaraba no kweza.Iyo ibicuruzwa bikoreshejwe, ibintu bya alkaline birashobora kongerwaho igisubizo cyibicuruzwa kugirango uhindure PH yumuti kugirango ube alkaline, kandi ibicuruzwa bishonga vuba mubisubizo.Ubu buryo burashobora kandi gukoreshwa mugihe igisubizo cya selulose ether gikoreshwa mugukora firime hanyuma firime ikavurwa kugirango ikore firime idashonga.
6, hydroxypropyl methyl selulose anti-enzyme
Hydroxypropyl methyl selulose enzyme irwanya ibikomoka kuri selile mu myumvire, nka buri tsinda rya anhydroglucose nkaho hari ihuriro rikomeye ryo gusimbuza amatsinda, isuri ya mikorobe ntishobora kwandura, ariko mubyukuri ibicuruzwa byarangiye kugirango bisimbuze agaciro karenze 1, nanone no kwangirika kwa enzyme, ibi nibisobanuro bya buri tsinda murwego rwo gusimbuza urunigi rwa selile ntabwo ari kimwe, Microorganisme irashobora kwangirika hafi yitsinda rya glucose idafite umwuma kugirango ibe isukari, ishobora kwinjizwa na mikorobe nkibiribwa.Kubwibyo, niba urwego rwo gusimbuza etherification ya selile yiyongereye, kurwanya eteri ya selulose ether kumasuri ya enzymatique biziyongera.Bivugwa ko mu bihe byagenzuwe, ubukonje busigaye bwa hydroxypropyl methyl selulose (DS = 1.9), methyl selulose (DS = 1.83), methyl selulose (DS = 1.66), na hydroxyethyl selulose (1,7%) yari 13.2%, 7.3% , 3.8%, na 1.7%.Hydroxypropyl methyl selulose ifite ubushobozi bukomeye bwo kurwanya enzyme.Hydroxypropyl methylcellulose nziza cyane anti-enzyme, ifatanije no gutatana kwayo neza, kubyimba no gukora firime, ikoreshwa mubitambaro bya emulsiya, nibindi, mubisanzwe ntabwo ikeneye kongeramo imiti igabanya ubukana.Ariko rero, kugirango hirindwe kubika igihe kirekire igisubizo cyangwa ibisubizo byanduye biturutse hanze, hashobora kongerwamo imiti igabanya ubukana, uwatoranijwe ashobora kugenwa hakurikijwe ibisabwa byanyuma.Fenilmercuric acetate na fluosilicate ya manganese birinda ibintu neza, ariko ni uburozi kandi bigomba gukoreshwa neza.Mubisanzwe, 1 ~ 5mg fenylmercuric acetate irashobora kongerwa kuri litiro yumuti.
7, hydroxypropyl methyl selulose membrane imikorere
Hydroxypropyl methyl selulose yerekana firime ya hydroxypropyl methyl selulose ifite firime nziza, igisubizo cyamazi cyayo cyangwa igisubizo cyumuti wumuti, ushyizwe kumasahani yikirahure, nyuma yo kumisha biba firime idafite ibara, ibonerana kandi ikomeye.Ifite ubushyuhe bwiza kandi ikomeza gukomera ku bushyuhe bwinshi.Nkokwongeramo plasitike ya hygroscopique, irashobora kongera uburebure bwayo no guhinduka, kugirango itezimbere flexure, glycerol na sorbitol nibindi bikoresho bya pulasitiki nibyo bikwiye.Igisubizo rusange cyibisubizo ni 2% ~ 3%, dosiye ya plastike ni 10% ~ 20% ya selile ya ether.Niba ibikubiye muri plasitike birenze urugero, ibintu bigabanuka byo kubura umwuma wa colloid birashobora kugaragara mubushuhe bwinshi.Imbaraga zingana za firime zongewemo plastike nini cyane kuruta iyo itongeweho, kandi yiyongera hamwe no kwiyongera kwinshi kongeweho, kuko kubijyanye na hygroscopicity ya firime nayo yiyongera hamwe no kwiyongera kwa plastike.
Igihe cyo kohereza: Nzeri-08-2022