HPMC cyangwa hydroxypropyl methylcellulose ni ibintu byinshi bikoreshwa mu nganda zitandukanye zirimo imiti, amavuta yo kwisiga n'ibiryo.Ikoreshwa cyane nkibyimbye na emulisiferi, kandi ububobere bwayo burahinduka bitewe nubushyuhe bugaragaramo.Muri iyi ngingo, tuzibanda ku isano iri hagati yubukonje nubushyuhe muri HPMC.
Viscosity isobanurwa nkigipimo cyamazi arwanya amazi.HPMC ni kimwe cya kabiri gikomeye igipimo cyo guhangana nacyo giterwa nibintu bitandukanye, harimo n'ubushyuhe.Kugira ngo twumve isano iri hagati yubukonje nubushyuhe muri HPMC, dukeneye mbere na mbere kumenya uko ibintu byakozwe nicyo bikozwe.
HPMC ikomoka kuri selile, isanzwe iba polymer mubimera.Kugirango habeho HPMC, selile igomba guhindurwa muburyo bwa chimique hamwe na okiside ya propylene na methyl chloride.Ihinduka rivamo gushiraho hydroxypropyl na methyl ether mumatsinda ya selile.Igisubizo ni ikintu cyakomeye gishobora gushonga mumazi no kumashanyarazi kama kandi bigakoreshwa muburyo butandukanye, harimo nk'igifuniko cyibinini ndetse nkibintu byongera ibiryo, nibindi.
Ubukonje bwa HPMC biterwa nubunini bwibintu hamwe nubushyuhe bugaragaramo.Muri rusange, ubwiza bwa HPMC buragabanuka hamwe no kwiyongera.Ibi bivuze ko kwibanda cyane kuri HPMC bivamo viscoscies nkeya naho ubundi.
Nyamara, isano itandukanye hagati yubukonje nubushyuhe biragoye.Nkuko byavuzwe haruguru, ubwiza bwa HPMC bwiyongera hamwe nubushyuhe bugabanuka.Ibi bivuze ko iyo HPMC ikorewe ubushyuhe buke, ubushobozi bwayo bwo gutemba buragabanuka kandi bikarushaho kuba byiza.Mu buryo nk'ubwo, iyo HPMC ikorewe ubushyuhe bwinshi, ubushobozi bwayo bwo kugenda bwiyongera kandi ubwiza bwayo bukagabanuka.
Hariho ibintu bitandukanye bigira ingaruka kumubano uri hagati yubushyuhe nubukonje muri HPMC.Kurugero, ibindi bisubizo biboneka mumazi birashobora kugira ingaruka kubwiza, kimwe na pH yamazi.Muri rusange ariko, hari isano itandukanye hagati yubukonje nubushyuhe muri HPMC bitewe ningaruka zubushyuhe kumubumbe wa hydrogène no guhuza molekile iminyururu ya selile muri HPMC.
Iyo HPMC ikorewe ubushyuhe buke, iminyururu ya selile iba ikomeye, bigatuma habaho guhuza hydrogene.Ihuriro rya hydrogène ritera ibintu birwanya ibintu gutembera, bityo bikongera ububobere bwayo.Ku rundi ruhande, iyo HPMCs yakorewe ubushyuhe bwinshi, iminyururu ya selile yarushijeho guhinduka, bigatuma habaho hydrogene nkeya.Ibi bigabanya imbaraga zo kurwanya ibintu gutemba, bikavamo ubukonje buke.
Birakwiye ko tumenya ko mugihe mubisanzwe hariho isano itandukanye hagati yubukonje nubushyuhe bwa HPMC, ntabwo buri gihe bigenda kumoko yose ya HPMC.Isano nyayo iri hagati yubukonje nubushyuhe irashobora gutandukana bitewe nuburyo bwo gukora nicyiciro cyihariye cya HPMC yakoreshejwe.
HPMC ni ibintu byinshi bikoreshwa cyane munganda zinyuranye kubyimbye no kwigana.Ubukonje bwa HPMC buterwa nibintu byinshi, harimo kwibumbira hamwe nubushyuhe bugaragaramo.Muri rusange, ubwiza bwa HPMC buringaniye nubushyuhe, bivuze ko uko ubushyuhe bugabanuka, ubukonje bwiyongera.Ibi biterwa n'ingaruka z'ubushyuhe kuri hydrogène ihuza hamwe na molekile ikora iminyururu ya selile muri HPMC.
Igihe cyo kohereza: Nzeri-08-2023