HPMC irashobora kugabanywa mubyiciro byubwubatsi, icyiciro cyibiribwa nicyiciro cya farumasi ukurikije intego.Kugeza ubu, ibyinshi mubicuruzwa byo murugo ni amanota yubwubatsi, kandi mubyiciro byubwubatsi, ingano yifu ya putty ni nini cyane.Kuvanga ifu ya HPMC hamwe ninshi mubindi bintu byifu yifu, ubivange neza na mixer, hanyuma wongeremo amazi kugirango ushonga, hanyuma HPMC irashobora gushonga muriki gihe nta agglomeration, kuko buri mfuruka ntoya, gakeya yifu ya HPMC, ihura amazi.izahita ishonga.Ifu yuzuye ifu nabakora minisiteri bakoresha ubu buryo.Hydroxypropyl methylcellulose (HPMC) ikoreshwa nk'umubyimba mwinshi kandi ugumana amazi muri minisiteri yifu ya putty.
Ubushyuhe bwa gel bwa HPMC bufitanye isano nuburyo bukubiyemo, munsi ya vitamine ↓, nubushyuhe bwa gel ↑.Ubwoko bwamazi akonje ako kanya HPMC ivurwa hejuru na glyoxal, kandi ikwirakwira vuba mumazi akonje, ariko ntabwo ishonga.Irashonga gusa iyo ububobere bwiyongereye.Ubwoko bushyushye ntibuboneka hejuru hamwe na glyoxal.Niba ingano ya glyoxal ari nini, gutatanya bizihuta, ariko ubwiza bwiyongera buhoro, kandi niba umubare ari muto, ibinyuranye bizaba ukuri.HPMC irashobora kugabanwa muburyo bwubwoko nubwoko bushyushye.Ubwoko bwibicuruzwa ako kanya bikwirakwira vuba mumazi akonje bikabura mumazi.Muri iki gihe, amazi ntagira ubwiza kuko HPMC ikwirakwizwa mumazi gusa nta gushonga nyabyo.Hafi yiminota 2, ubwiza bwamazi bugenda bwiyongera buhoro buhoro, bukora colloid ibonerana.Ibicuruzwa bishyushye, iyo bihuye namazi akonje, birashobora gukwirakwira vuba mumazi ashyushye bikabura mumazi ashyushye.Iyo ubushyuhe bugabanutse ku bushyuhe runaka, ibishishwa bizagaragara buhoro buhoro kugeza igihe bibumbiye mu mucyo.Ubwoko bushyushye burashobora gukoreshwa gusa mubifu ya pome na minisiteri.Muri kole yamazi no gusiga irangi, hazabaho guterana ibintu kandi ntibishobora gukoreshwa.Ubwoko bwakanya bufite intera yagutse ya porogaramu.Irashobora gukoreshwa mu ifu yuzuye ifu na minisiteri, hamwe na kole yamazi hamwe n irangi, nta kubuza.
HPMC yakozwe nuburyo bwo gukemura ikoresha toluene na isopropanol nkibishishwa.Niba gukaraba atari byiza cyane, hazabaho umunuko usigaye.Gukoresha ifu ya putty: ibisabwa ni bike, viscosity ni 100.000, birahagije, icyangombwa nukubungabunga amazi neza.Gukoresha minisiteri: ibisabwa hejuru, viscosity nyinshi, 150.000 nibyiza.Gukoresha kole: ibicuruzwa byihuse hamwe nubwiza bwinshi birasabwa.Ingano ya HPMC ikoreshwa mubikorwa bifatika iratandukanye bitewe nikirere cyikirere, ubushyuhe, ubwiza bwa calcium y ivu ryaho, ifu yifu yifu n "ubuziranenge busabwa nabakiriya".Ubukonje bwa hydroxypropyl methylcellulose (HPMC) -ifu yinjiza muri rusange ni 100.000, kandi ibisabwa kuri minisiteri ni byinshi, kandi bikenera 150.000 kugirango byoroshye gukoresha.Byongeye kandi, imikorere nyamukuru ya HPMC ni ukubika amazi, hagakurikiraho kubyimba.Mu ifu ya putty, mugihe cyose gufata amazi ari byiza kandi ibishishwa bikaba bike (70.000-80,000), birashoboka.Birumvikana ko hejuru yubukonje, niko gufata amazi ugereranije.Iyo ibishishwa birenze 100.000, ubwiza buzagira ingaruka kumazi.Ntabwo ari byinshi;abafite hydroxypropyl nyinshi muri rusange bafite amazi meza.Iyifite ubukonje bwinshi ifite uburyo bwiza bwo gufata amazi, naho iyifite ubukonje bwinshi ikoreshwa neza muri sima ya sima.
Ifu yuzuye, HPMC ifite uruhare runini rwo kubyimba, gufata amazi no kubaka.Ntukagire uruhare mubitekerezo byose.Impamvu yibibyimba irashobora kuba ishyizwemo amazi menshi, cyangwa birashoboka ko igice cyo hasi kitumye, kandi ikindi gice cyashizwe hejuru, kandi byoroshye kubira ifuro.Ingaruka yibyibushye ya HPMC mu ifu yuzuye: selile irashobora kuba mwinshi kugirango ihagarike, igumane igisubizo kimwe kandi gihamye, kandi irinde kugabanuka.Ingaruka yo gufata amazi ya HPMC mu ifu ya putty: kora ifu ya putty yumye gahoro gahoro, kandi ufashe calcium yivu gukora mugihe cyamazi.Ingaruka yubwubatsi bwa HPMC mu ifu yuzuye: selile ifite ingaruka zo gusiga, zishobora gutuma ifu ya putty yubaka neza.HPMC ntabwo yitabira imiti iyo ari yo yose, ariko igira uruhare gusa.
Gutakaza ifu yifu ya putty bifitanye isano ahanini nubwiza bwa calcium yivu, kandi ntaho bihuriye na HPMC.Kalisiyumu nkeya ya calcium yumukara hamwe nigipimo kidakwiye cya CaO na Ca (OH) 2 muri calcium yumukara bizatera gutakaza ifu.Niba bifite aho bihuriye na HPMC, noneho niba gufata amazi ya HPMC ari bibi, bizanatuma ifu igwa.Kongera amazi kumafu ya putty ukayashyira kurukuta ni reaction ya chimique, kuko havutse ibintu bishya, kandi ifu ya putty kurukuta ikurwa kurukuta.Hasi, hasi mubifu, hanyuma ukoreshe, ntabwo bizakora, kuko ibintu bishya (calcium karubone) byakozwe.Ibice byingenzi bigize ifu ya calcium yivu ni: imvange ya Ca (OH) 2, CaO hamwe na CaCO3 nkeya, CaO + H2O = Ca (OH) 2 - Ca (OH) 2 + CO2 = CaCO3 ↓ + H2O Kalisiyumu yivu iri mumazi no mwuka Mubikorwa bya CO2, karubone ya calcium ikorwa, mugihe HPMC igumana amazi gusa, ifasha reaction nziza ya calcium yivu, kandi ntabwo yitabira reaction ubwayo.
Igihe cyo kohereza: Werurwe-18-2023