Hydroxypropyl methylcellulose (HPMC) ni polymer itandukanye ikoreshwa cyane mu nganda zitandukanye kubera imiterere n'imikorere idasanzwe.Iyi polymer ya santetike ikomoka kuri selile, polymer karemano iboneka murukuta rwibimera.HPMC ikorwa muguhindura selile binyuze muri etherification ya oxyde ya propylene na methyl chloride.Polimeri yavuyemo yerekana urutonde rwimitungo yifuzwa, bigatuma ikoreshwa muburyo butandukanye.Ubu buryo bugari bwo gukoresha bushobora kwitirirwa ubushobozi bwo gukora firime, kubyimba ibintu, gutuza mubidukikije bitandukanye hamwe na biocompatibilité.
1. Inganda zimiti
A. Ubuyobozi bwo mu kanwa:
Kurekurwa kugenzurwa: HPMC isanzwe ikoreshwa mugutanga imiti igenzurwa mugutanga imiti.Ikora matrix ihamye ituma irekurwa ryimiti igenzurwa mugihe kinini, bityo bigatuma imiti ivura no kubahiriza abarwayi.
Guhuza ibinini: HPMC ikora nkibikoresho bifatika kandi bifasha mugukora ibinini bifite imbaraga za mashini hamwe no gusenya.
Umukozi uhagarika: Muburyo bwa dosiye yamazi, HPMC ikora nkumukozi uhagarika, ibuza uduce gutuza kandi ikwirakwiza ibiyobyabwenge kimwe.
B. Amaso yubuvuzi:
Guhindura Viscosity: HPMC ikoreshwa muguhindura ubwiza bwibitonyanga byamaso kugirango itange amavuta meza kandi itume igihe kinini cyo guhura hejuru yijisho.
Abakora firime: bikoreshwa mugukora masike yijisho cyangwa gushiramo kugirango irekure rihoraho ryibiyobyabwenge mumaso.
C. Imyiteguro yibanze:
Imiterere ya Gel: HPMC ikoreshwa mugutegura geles yibanze itanga uburyo bworoshye, butarimo amavuta no kunoza kubahiriza abarwayi.
Uruhu rwuruhu: Muri sisitemu yo gutanga imiti ya transdermal, HPMC itanga imiti ifata kandi igenzura irekurwa ryibiyobyabwenge binyuze muruhu.
D. Ibimera bishobora kwangirika:
Ibikoresho bya Scaffold: HPMC ikoreshwa mugukora ibinyabuzima byangiza umubiri bigenzura irekurwa ryibiyobyabwenge mumubiri, bikuraho gukenera kubagwa.
Inganda zubaka
A. Amatafari:
Thickener: HPMC ikoreshwa nkibyimbye mumatafari ya tile kugirango itange ibisabwa bikenewe kugirango byoroshye gukoreshwa.
Kubika Amazi: Yongera imbaraga zo gufata amazi yifata, ikayirinda gukama vuba kandi igakira neza.
B. Isima ya sima:
Imikorere: HPMC ikora nkimpinduka ya rheologiya kugirango ikumire amacakubiri kandi itezimbere ubumwe, bityo bitezimbere imikorere ya minisiteri ishingiye kuri sima.
Kubika Amazi: Bisa na tile yifata, ifasha kugumana ubuhehere muruvange rwa sima, bigatuma habaho amazi meza kandi bigatera imbere.
3. inganda zibiribwa
A. Ibiryo byongera ibiryo:
Thickeners and Stabilizers: HPMC ikoreshwa nkibibyibushye kandi bigahindura ibicuruzwa bitandukanye byibiribwa, nka sosi, imyambarire hamwe nubutayu.
Gusimbuza ibinure: Mu biribwa birimo ibinure bike cyangwa bidafite amavuta, HPMC irashobora gukoreshwa nkibisimbuza ibinure kugirango byongere ubwiza bwumunwa.
4. Inganda zo kwisiga
A. Ibicuruzwa byita ku muntu:
Igenzura rya Viscosity: HPMC ikoreshwa muburyo bwo kwisiga nk'amavuta yo kwisiga hamwe na cream kugirango bigabanye ububobere no kunoza imiterere rusange.
Abakora firime: Fasha gukora firime mubicuruzwa byita kumisatsi, bitanga urwego rukingira.
5. Ibindi bikorwa
A. Gucapa wino:
Thickener: HPMC ikoreshwa nkibyimbye mumazi ashingiye kumazi yo gucapa kugirango ifashe kugera kumurongo wifuzwa kandi uhamye.
B. Ibicuruzwa bifata neza:
Kunoza ibishishwa: Mubisobanuro bifatika, HPMC irashobora kongerwamo kugirango yongere ubwiza no kunoza imikoranire.
5. mu gusoza
Porogaramu zitandukanye za HPMC mu nganda zinyuranye zigaragaza byinshi kandi bifatika.Ikoreshwa ryayo muri farumasi, ubwubatsi, ibiryo, kwisiga nizindi nzego byerekana ihuza ryihariye ryimitungo, harimo ubushobozi bwo gukora firime, kubyimba no gutuza.Mugihe ikoranabuhanga nubushakashatsi bigenda bitera imbere, HPMC birashoboka ko izakomeza kugira uruhare runini mugutezimbere ibicuruzwa bishya nibikorwa bishya mubice bitandukanye.
Igihe cyo kohereza: Gashyantare-07-2024