Hydroxypropyl Methyl Cellulose (HPMC), izwi kandi ku izina ry'ubucuruzi hypromellose, ni polymer synthique ikomoka kuri selile naturel. Inkomoko yibanze ya selile yo gukora HPMC mubisanzwe ni ibiti cyangwa ipamba. Igikorwa cyo gukora kirimo guhindura imiti ya selile binyuze muri etherification, kwinjiza hydroxypropyl na methyl mumatsinda ya selile.

Umusaruro wa HPMC urimo intambwe nyinshi:

1. Gukuramo Cellulose:
   • Cellulose iboneka mu bimera, cyane cyane ibiti cyangwa ipamba. Cellulose ikuramo kandi igasukurwa kugirango ibe selile.
2. Alkalisation:
   • Indwara ya selulose ivurwa n'umuti wa alkaline, ubusanzwe hydroxide ya sodium (NaOH), kugirango itangire amatsinda ya hydroxyl kumurongo wa selile.
3. Etherification:
   • Etherification nintambwe yingenzi mubikorwa bya HPMC. Selulose ya alkalize ikorwa na oxyde ya propylene (kumatsinda ya hydroxypropyl) na methyl chloride (kumatsinda ya methyl) kugirango yinjize ayo matsinda ya ether kumugongo wa selile.
4. Kutabogama no Gukaraba:
   • Cellulose yahinduwe yavuyemo, ubu ni Hydroxypropyl Methyl Cellulose, ikora inzira yo kutabogama kugirango ikureho alkali isigaye. Hanyuma irakaraba neza kugirango ikureho umwanda nibicuruzwa.
5. Kuma no gusya:
   • Cellulose yahinduwe yumishijwe kugirango ikureho ubuhehere burenze hanyuma isya mu ifu nziza. Ingano yingingo irashobora kugenzurwa hashingiwe kubisabwa.

Ibicuruzwa bya HPMC bivamo ni ifu yera cyangwa yera-yera ifite impamyabumenyi zitandukanye za hydroxypropyl na methyl. Imiterere yihariye ya HPMC, nkibishobora gukemuka, kwiyegeranya, nibindi biranga imikorere, biterwa nurwego rwo gusimburwa nuburyo bwo gukora.

Ni ngombwa kumenya ko HPMC ari igice cya sintetike ya polymer, kandi mugihe ikomoka kuri selile karemano, ihindura imiti ihambaye mugihe cyogukora kugirango igere kubintu byifuzwa mubikorwa bitandukanye byinganda.