Carboxymethylcellulose (CMC) na methylcellulose (MC) byombi bikomoka kuri selile, polymer karemano iboneka murukuta rw'utugingo ngengabuzima. Ibikomokaho usanga bikoreshwa cyane mubikorwa bitandukanye bitewe nimiterere yihariye. Nubwo basangiye ibintu, CMC na MC bifite itandukaniro ritandukanye muburyo bwa shimi, imiterere, imikoreshereze, hamwe ninganda zikoreshwa.
1.Imiterere yimiti:
Carboxymethylcellulose (CMC):
CMC ikomatanyirizwa hamwe na etherification ya selile hamwe na aside ya chloroacetic, bigatuma habaho gusimbuza amatsinda ya hydroxyl (-OH) kumugongo wa selile hamwe nitsinda rya carboxymethyl (-CH2COOH).
Urwego rwo gusimbuza (DS) muri CMC bivuga impuzandengo yimibare ya carboxymethyl kumatsinda ya glucose murwego rwa selile. Iyi parameter igena imiterere ya CMC, harimo kwikemurira ibibazo, ubwiza, nimyitwarire ya rheologiya.
Methylcellulose (MC):
MC ikorwa no gusimbuza hydroxyl mumatsinda ya selile hamwe na methyl matsinda (-CH3) binyuze muri etherification.
Kimwe na CMC, imitungo ya MC iterwa nurwego rwo gusimbuza, igena urugero rwa methylation kumurongo wa selile.
2.Ubushake:
Carboxymethylcellulose (CMC):
CMC ibora mumazi kandi ikora ibisubizo biboneye, bigaragara neza.
Gukemura kwayo ni pH-biterwa, hamwe no gukomera kwinshi mubihe bya alkaline.
Methylcellulose (MC):
MC nayo irashonga mumazi, ariko gukemura kwayo biterwa nubushyuhe.
Iyo yashonze mumazi akonje, MC ikora gel, igashonga bidasubirwaho iyo ishyushye. Uyu mutungo utuma bikwiranye na porogaramu zisaba gelation igenzurwa.
3.Ubushishozi:
CMC:
Yerekana ububobere buke mubisubizo byamazi, bigira uruhare mubwinshi bwabyo.
Ubukonje bwacyo burashobora guhindurwa muguhindura ibintu nko kwibanda, urwego rwo gusimburwa, na pH.
MC:
Yerekana imyitwarire yubusa isa na CMC ariko muri rusange ntigaragara neza.
Ubwiza bwibisubizo bya MC burashobora kandi kugenzurwa no guhindura ibipimo nkubushyuhe hamwe nubushuhe.
4.Gushiraho Filime:
CMC:
Gukora firime zisobanutse, zoroshye iyo zashizwe mubisubizo byamazi.
Izi firime zisanga porogaramu mu nganda nko gupakira ibiryo na farumasi.
MC:
Irashoboye kandi gukora firime ariko ikunda gucika intege ugereranije na firime ya CMC.
5. Inganda nziza:
CMC:
Byakoreshejwe cyane nka stabilisateur, kubyimbye, na emulisiferi mubicuruzwa byibiribwa nka ice cream, isosi, hamwe no kwambara.
Ubushobozi bwayo bwo guhindura imiterere hamwe numunwa wibiribwa bituma bigira agaciro mubiribwa.
MC:
Byakoreshejwe mubikorwa bisa na CMC mubicuruzwa byibiribwa, cyane cyane mubisabwa bisaba gukora gel no guhagarara neza.
6.Imiti:
CMC:
Byakoreshejwe muburyo bwa farumasi nka binder, disintegrant, na viscosity modifier mugukora tablet.
Ikoreshwa kandi mubikorwa byingenzi nka cream na geles bitewe nimiterere yabyo.
MC:
Bikunze gukoreshwa nkibintu byongera umubyimba muri farumasi, cyane cyane mumiti yamazi yo mumanwa hamwe nibisubizo byamaso.
7.Ibicuruzwa byita ku bantu:
CMC:
Biboneka mubintu bitandukanye byita kumuntu nka menyo yinyo, shampoo, hamwe namavuta yo kwisiga nka stabilisateur kandi ikabyimba.
MC:
Byakoreshejwe mubisabwa bisa na CMC, bigira uruhare muburyo bwimiterere no gutuza kwawe.
8.Ibisabwa mu nganda:
CMC:
Akoreshwa mu nganda nk'imyenda, impapuro, na ceramika kubera ubushobozi bwayo bwo gukora nk'ibikoresho, bihindura imvugo, hamwe n'umukozi ushinzwe gufata amazi.
MC:
Shakisha ikoreshwa mubikoresho byubwubatsi, amarangi, hamwe nibifatika kubera kubyimbye no guhuza ibintu.
mugihe carboxymethylcellulose (CMC) na methylcellulose (MC) byombi bikomoka kuri selile hamwe nibikorwa bitandukanye byinganda, bagaragaza itandukaniro mumiterere yimiti yabo, imyitwarire yo kwikemurira ibibazo, imyirondoro yubusa, hamwe nibisabwa. Gusobanukirwa iri tandukaniro ningirakamaro muguhitamo inkomoko ikwiye gukoreshwa muburyo butandukanye mu nganda zitandukanye, uhereye ku biribwa na farumasi kugeza ku muntu ku giti cye ndetse no mu nganda. Byaba bikenewe kubyimbye bya pH nka CMC mubicuruzwa byibiribwa cyangwa imiti itanga ubushyuhe nka MC muburyo bwa farumasi, buri nkomoko itanga inyungu zidasanzwe zijyanye nibisabwa byihariye mubice bitandukanye.
Igihe cyo kohereza: Werurwe-22-2024