Niki hypromellose ikoreshwa mubinini?

Hypromellose, izwi kandi nka hydroxypropyl methylcellulose (HPMC), ikoreshwa muburyo bwa tableti kubintu byinshi:

1. Binder: HPMC ikoreshwa kenshi muguhuza ibinini kugirango ibashe gufata imiti ikora (APIs) hamwe nibindi bicuruzwa hamwe. Nka binder, HPMC ifasha gukora ibinini bifatanye hamwe nimbaraga zihagije za mashini, byemeza ko tablet ikomeza ubusugire bwayo mugihe cyo kuyitunganya, kuyipakira, no kubika.
2. Disintegrant: Usibye imiterere ihuza, HPMC irashobora kandi gukora nkibidahwitse mubinini. Disintegrants zifasha guteza imbere kwangirika cyangwa gusenyuka vuba kwa tablet ukimara kurya, bikorohereza kurekura ibiyobyabwenge no kwinjirira mumitsi yigifu. HPMC irabyimba vuba iyo ihuye n’amazi, biganisha ku kumenagura ibinini mo uduce duto kandi bifasha mu gusesa ibiyobyabwenge.
3. Firime Yahoze / Umukozi wa Coating: HPMC irashobora gukoreshwa nkumukozi ukora firime cyangwa ibikoresho byo gutwikira ibinini. Iyo ushyizwe muri firime yoroheje hejuru ya tablet, HPMC ifasha kunoza isura, kumira, no gutuza kwa tablet. Irashobora kandi kuba inzitizi yo kurinda ibinini amazi, urumuri, hamwe n’imyuka yo mu kirere, bityo bikongerera ubuzima ubuzima kandi bikarinda imbaraga z’ibiyobyabwenge.
4. Matrix Yahoze: Mugenzuzi-kurekura cyangwa gukomeza-kurekura ibinini bya tablet, HPMC ikoreshwa nka matrix yambere. Nka matrise yahoze, HPMC igenzura irekurwa ryibiyobyabwenge ikora matrix isa na gel ikikije API, igenga igipimo cyayo cyo kuyisohora mugihe kinini. Ibi bituma imiti igenzurwa no kunoza iyubahirizwa ry’abarwayi kugabanya inshuro nyinshi.
5. Ibyingenzi: HPMC irashobora kandi gukoreshwa nkibintu byoroshye mugutegura ibinini kugirango ihindure imiterere yikibaho, nko gukomera, gucika intege, nigipimo cyo gusesa. Imiterere yacyo itandukanye ituma ikoreshwa muburyo butandukanye, harimo guhita-kurekura, gutinda-kurekurwa, hamwe no kwagura-kurekura ibinini.

Muri rusange, HPMC ni imiti ikoreshwa cyane mu miti ya tablet bitewe na biocompatibilité, ihindagurika, hamwe ningirakamaro mugushikira imitungo yifuzwa. Imiterere yimikorere myinshi ituma abayitegura bashushanya ibinini byujuje ibisabwa kugirango batange imiti nibisabwa abarwayi.