kumenyekanisha
Abahanga muri Celefoni ni polymes y'amazi ya aiyoni yakomokaga kuri selile. Izi polymer zifite porogaramu nyinshi mu nganda zinyuranye nk'ibiryo, imiti, kwisiga, no kubaka, ngo bibe imitungo yabo nko kubyimba, gushiraho filimi, no gukata firime. Kimwe mu bintu by'ingenzi bya elever of selile ni ubushyuhe bwa gelation yubushyuhe (tg), ubushyuhe aho polymer ihura ninzibacyuho yicyiciro kuva sol kuri Gel. Uyu mutungo ni ukomeye muguhitamo imikorere ya ba elerare selile muburyo butandukanye. Muri iyi ngingo, tuganira ku bushyuhe bwa gelation ya hydroxyproppopyl methylcellse (HPMC), kimwe mu bahitamo ka selile bakunze gukoreshwa mu nganda.
Ubushyuhe bwa gelation ya HPMC
HPMC ni igice cya seliki ya eliegite yakoreshejwe cyane muburyo butandukanye kubera imitungo yihariye. HPMC irashonje cyane mumazi, ikora ibisubizo bya viscous bisakuza. Mugihe kinini, HPMC igipapuro cya gels ihinduka nyuma yo gushyushya no gukonjesha. Ubushyuhe bwa HPMC bwa HPMC nintambwe ebyiri zirimo gushiraho miselle yakurikijwe no guteranya miselle kugirango imiseri ikore umuyoboro wa gel (Ishusho 1).
Ubushyuhe bwa gelation yubushyuhe bwa HPMC biterwa nibintu byinshi nkurwego rwo gusimbuza (DS), uburemere bwa moleki, kwibanda, na ph of igisubizo. Muri rusange, hejuru ya DS hamwe nuburemere bwa moleclar ya HPMC, hejuru yubushyuhe bwa gelation yubushyuhe. Kwibanda kuri HPMC mubisubizo kandi bigira ingaruka kuri TG, hejuru yibandaho, hejuru tg. PH yo mu gisubizo kandi bigira ingaruka kuri tg, hamwe n'ibisubizo bya acide bivamo tg.
Ingano yubushyuhe ya HPMC irahinduka kandi irashobora kugira ingaruka kubintu bitandukanye byo hanze nko gukomera, ubushyuhe, nubushyuhe bwumunyu. Shear yamenaguye imiterere kandi igabanya TG, nubwo ubushyuhe butera umupaka gushonga no kugabanya tg. Ongeraho umunyu kumuti kandi ugira ingaruka kuri TG, kandi kuboneka kwa calcium nka calcium na magnesium byongera tg.
Gushyira mu bikorwa TG itandukanye HPMC
Imyitwarire ya TheRongill ya HPMC irashobora guhuzagurika kubisabwa bitandukanye. HG HP HPMC ikoreshwa mubisabwa isaba peleti yihuta, nka dessert ako kanya, isosi hamwe nisupu. HPMC hamwe na tg ndende ikoreshwa mubisabwa kimwe na gelation yatinze cyangwa ndende, nko gushyiraho sisitemu yo gutanga ibiyobyabwenge, birekura ibisate birekura ibiyobyabwenge, no kwambara ibikomere.
Mu nganda zibiribwa, HPMC ikoreshwa nkuwabyimbye, stabilizer na umukozi wa dolling. Hasi ya TG HPMC ikoreshwa mu mashusho atoroshye asaba peleti yihuta kugirango itange imiterere yifuzwa n'umunwa. HPMC hamwe na tg ndende ikoreshwa mumashusho make yakwirakwijwe aho hatizwa pelage yatinze cyangwa ndende byifuzwa gukumira syneresis no gukomeza imiterere ikwirakwiza.
Mu nganda za farumasi, HPMC ikoreshwa nka binder, itunganijwe kandi irambye irekurwa. HPMC hamwe na tg ndende ikoreshwa mugushiraho ibinini byagutse, aho pelati yatinze cyangwa ndende isabwa kurekura ibiyobyabwenge mugihe kinini. Hasi ya TG HPMC ikoreshwa mu gushyiraho ibinini byo gusenya umunwa, aho gusenyuka byihuse kandi pelation isabwa gutanga umunwa wifuzwa no korohereza kumira.
Mu gusoza
Ubushyuhe bwa gelation yubushyuhe bwa HPMC numutungo wingenzi ugena imyitwarire yayo muburyo butandukanye. HPMC irashobora guhindura tg yayo binyuze murwego rwo gusimbuza, uburemere bwa moleki, kwibanda hamwe na pH agaciro k'ibisubizo kugirango bikwiranye na porogaramu zitandukanye. HPMC hamwe na tg nkeya zikoreshwa mubisabwa bisaba gufata ibyemezo byihuse, mugihe HPMC ifite tg ndende ikoreshwa mubisabwa isaba peliolation yatinze cyangwa ndende. HPMC ni uguhuza na selile itandukanye kandi itandukanye hamwe nibishoboka byinshi mubintu bitandukanye.
Igihe cya nyuma: Kanama-24-2023