Umubano hagati yo kugumana namazi nubushyuhe bwa HPMC

1. Imiterere n'imiterere yo kugumana amazi ya HPMC

HPMC ikorwa no guhindura imiti ya selile karemano, ahanini no gutangiza hydroxyproppopyl (-C3h7oh) na methyl (-Ch3) mumatsinda ya selile, ayiha umukecuru. Amatsinda ya Hydroxyl (-Oh) muri molekile ya HPMC irashobora gukora hydrogen ingwate na molekile yamazi. Kubwibyo, HPMC irashobora gukurura amazi no guhuza n'amazi, yerekana kugumana amazi.

 

Kugumana amazi bivuga ubushobozi bwikintu cyo kugumana amazi. Kuri HPMC, igaragara cyane mubushobozi bwayo bwo kubungabunga amazi muri sisitemu binyuze muri hydration, cyane cyane mubushyuhe cyangwa ubushyuhe bwinshi, bushobora kubuza neza amazi yihuta kandi bikagumana uburemere bwibintu. Kubera ko hydration muri molekile ya HPMC ifitanye isano rya bugufi nuburyo bwo gukora imiterere yacyo, impinduka zubushyuhe zizagira ingaruka ku bushobozi bwo kwinjiza amazi no kugumana amazi ya HPMC.

 

2. Ingaruka z'ubushyuhe bwo kugumana amazi ya HPMC

Umubano hagati yo kugumana amazi ya HPMC nubushyuhe birashobora kuganirwaho mubice bibiri: kimwe ningaruka zubushyuhe bworoshye bwa HPMC, naho ubundi ni ingaruka zubushyuhe kumiterere yacyo.

 

2.1 Ingaruka zubushyuhe kuri Logibility ya HPMC

Kudakemurwa na HPMC mumazi bifitanye isano n'ubushyuhe. Mubisanzwe, ibibazo byo kwiyongera kwa HPMC biyongera hamwe nubushyuhe bwongera ubushyuhe. Iyo ubushyuhe buzamutse, molekile y'amazi yunguka imbaraga zubushyuhe, bikaviramo intege nke yimikoranire hagati ya molekile y'amazi, bityo bigangiza iseswa rya Hpmc. Kuri HPMC, kwiyongera k'ubushyuhe birashobora koroha gushinga igisubizo cya colloidal, bityo bigahuza amazi.

 

Ariko, ubushyuhe bwinshi bushobora kongera vicosiya igisubizo cya HPMC, bigira ingaruka kumiterere ya motelelogiya no kudacogora. Nubwo iyi ngaruka nziza yo kunoza ibibazo byonyine, ubushyuhe bwinshi bushobora guhindura ituze ryurugero rwa molekeri kandi bigatuma habaho kugabanuka kwamazi.

 

2.2 Ingaruka zubushyuhe kumiterere ya molecular ya HPMC

Muburyo bwa HPMC, ingwate za hydrogen cyane zifite molekile y'amazi binyuze mumatsinda ya hydroxyl, kandi iyi mvange ya hydrogen ni ingenzi mu kugumana amazi ya HPMC. Mugihe ubushyuhe bwiyongera, imbaraga za hydrogen irashobora guhinduka, bikaviramo intege nke zimbaraga zidahuza na molekile ya HPMC, bityo molekile y'amazi, bityo ikagira ingaruka kumazi. By'umwihariko, ubwiyongere bwubushyuhe buzatera imyuga ya hydrogen muri molekile ya HPMC kugirango itandukane, bityo igabanye ubushobozi bwayo no kugumana amazi.

 

Byongeye kandi, ubushyuhe bwa HPMC bugaragarira kandi mubikorwa byicyiciro cyicyifuzo cyayo. HPMC hamwe nuburemere butandukanye bwa molekari hamwe nitsinda ritandukanye risimburwa rifite ubukana butandukanye. Muri rusange, uburemere bwa molecular buke HPMC bwumva ubushyuhe, mugihe uburemere bwa molecular bukabije HPMC yerekana imikorere ihamye. Kubwibyo, mubikorwa bifatika, birakenewe guhitamo ubwoko bwa HPMC bukwiye ukurikije ubushyuhe bwihariye kugirango hamenyekane amazi kumurimo wakazi.

 

2.3 Ingaruka zubushyuhe kumazi

Mu bushyuhe bwo hejuru, kugumana amazi bya HPMC bizagira ingaruka ku guhumeka amazi yihuta byatewe no kwiyongera k'ubushyuhe. Iyo ubushyuhe bwo hanze ari hejuru cyane, amazi muri sisitemu ya HPMC birashoboka cyane ko yangiza. Nubwo HPMC ishobora kugumana amazi kurwego runaka binyuze mumiterere yacyo, ubushyuhe bwinshi bushobora gutuma sisitemu itakaza amazi byihuse kuruta ubushobozi bwo kugumana mumazi ya HPMC. Muri iki gihe, kugumana amazi ya HPMC birabujijwe, cyane cyane mubushyuhe bwinshi nibidukikije byumye.

 

Kugirango ugabanye iki kibazo, ubushakashatsi bumwe bwerekanye ko bwongeraho abafite abafite abafite abafite abafite abafite abafite abafite abafite ubumenyi bukwiye cyangwa bagahindura ibindi bice muri formula birashobora kunoza ingaruka za HPMC mubushyuhe bwinshi. Kurugero, muguhindura uburyo bwo guhindura virusire muri formula cyangwa guhitamo igisubizo gihuha, kugumana amazi birashobora kunozwa kurwego runaka, kugabanya ingaruka z'ubushyuhe bwo kwiyongera k'amazi.