Acide hypromellose irwanya?

Hypromellose, izwi kandi nka hydroxypropyl methylcellulose (HPMC), ntabwo irwanya aside. Nyamara, aside irwanya hypromellose irashobora kongererwa imbaraga muburyo butandukanye bwo gukora.

Hypromellose irashobora gushonga mumazi ariko ntigishobora gukemuka mumashanyarazi kama namazi adafite inkingi. Kubwibyo, mubidukikije bya acide, nkigifu, hypromellose irashobora gushonga cyangwa kubyimba kurwego runaka, bitewe nibintu nko kwibumbira hamwe kwa aside, pH, hamwe nigihe bimara.

Kugirango tunoze aside irwanya hypromellose muburyo bwa farumasi, hakoreshwa uburyo bwo gutwika enteric. Enteric coatings ikoreshwa mubinini cyangwa capsules kugirango ibarinde aside irike yigifu kandi ibemerera kunyura mubidukikije bidafite aho bibogamiye mu mara mato mbere yo kurekura ibintu bikora.

Ububiko bwa enteric busanzwe bukozwe muri polymers irwanya aside gastricike, nka selulose acetate phthalate (CAP), hydroxypropyl methylcellulose phthalate (HPMCP), cyangwa polyvinyl acetate phthalate (PVAP). Izi polymers zikora inzitizi irinda ibinini cyangwa capsule, bikarinda gusenyuka hakiri kare cyangwa kwangirika mu gifu.

Muri make, mugihe hypromellose ubwayo idashobora kurwanya aside, irwanya aside irashobora kongerwa binyuze muburyo bwo gukora nka enteric. Ubu buhanga bukoreshwa muburyo bwa farumasi kugirango harebwe neza uburyo bwogukora neza kubintu bigenewe gukorerwa mumubiri.