HPMC ni hydrophobique cyangwa hydrophilique?

Hydroxypropyl methylcellulose (HPMC) ni polymer itandukanye ifite hydrophobique na hydrophilique, bigatuma idasanzwe mubikorwa bitandukanye mubikorwa bitandukanye. Kugirango twumve hydrophobicity na hydrophilicity ya HPMC, dukeneye kwiga imiterere, imiterere nibikorwa byimbitse.

Imiterere ya hydroxypropyl methylcellulose:

HPMC ikomoka kuri selile, polymer karemano iboneka murukuta rw'ibimera. Guhindura selile birimo kwinjiza hydroxypropyl na methyl mumatsinda ya selile. Ihinduka rihindura imiterere ya polymer, itanga imitungo yihariye ifitiye akamaro kanini porogaramu.

Hydrophilicity ya HPMC:

Hydroxy:

HPMC irimo hydroxypropyl matsinda kandi ni hydrophilique. Aya matsinda ya hydroxyl afite aho ahurira na molekile zamazi kubera guhuza hydrogen.

Itsinda rya Hydroxypropyl rishobora gukora hydrogène hamwe na molekile zamazi, bigatuma HPMC ishonga mumazi kurwego runaka.

methyl:

Mugihe itsinda rya methyl rigira uruhare muri hydrophobique muri rusange ya molekile, ntabwo irwanya hydrophilicity ya hydroxypropyl.

Itsinda rya methyl risa nkaho ridafite inkingi, ariko kuba itsinda rya hydroxypropyl rigena imiterere ya hydrophilique.

Hydrophobicity ya HPMC:

methyl:

Amatsinda ya methyl muri HPMC agena kurwego runaka hydrophobicity.

Nubwo atari hydrophobique nka polimeri zimwe na zimwe zuzuye, kuba amatsinda ya methyl bigabanya hydrophilicity muri HPMC.

Imiterere ya firime:

HPMC izwiho gukora firime kandi akenshi ikoreshwa mubikoresho bya farumasi no kwisiga. Hydrophobicity igira uruhare mu gushiraho firime ikingira.

Imikoranire nibintu bitari inkingi:

Mubisabwa bimwe, HPMC irashobora gukorana nibintu bitari polar bitewe na hydrophobic igice cyayo. Uyu mutungo ningirakamaro kuri sisitemu yo gutanga imiti munganda zimiti.

Porogaramu ya HPMC:

ibiyobyabwenge:

HPMC ikoreshwa cyane muburyo bwa farumasi nka binder, firime yahoze, hamwe na viscosity modifier. Ubushobozi bwayo bwo gukora firime byoroshya kurekura ibiyobyabwenge.

Irakoreshwa muburyo bukomeye bwa dosiye nkibinini na capsules.

Inganda zubaka:

Mu rwego rwubwubatsi, HPMC ikoreshwa mubicuruzwa bishingiye kuri sima kugirango bitezimbere imikorere, gufata amazi no gufatira hamwe.

Hydrophilicity ifasha kugumana amazi, mugihe hydrophobicity ifasha kunoza neza.

inganda z'ibiribwa:

HPMC ikoreshwa nkibintu byongera umubyimba mu nganda zibiribwa. Imiterere ya hydrophilique ifasha gukora geles ihamye no kugenzura ubwiza bwibicuruzwa byibiribwa.

kwisiga:

Mu kwisiga, HPMC ikoreshwa mubicuruzwa nka cream n'amavuta yo kwisiga kubera imiterere ya firime no kubyimba.

Hydrophilicity itanga neza neza uruhu.

mu gusoza:

HPMC ni polymer ari hydrophilique na hydrophobique. Iringaniza hagati ya hydroxypropyl na methyl matsinda muburyo bwayo itanga impinduramatwara idasanzwe, iyemerera kugira uburyo bwinshi bwo gusaba. Gusobanukirwa iyi mitungo ningirakamaro muguhuza HPMC kumikoreshereze yihariye munganda zitandukanye, aho ubushobozi bwa HPMC bwo gukorana namazi nibintu bidafite inkingi bikoreshwa mubikorwa bitandukanye.