HPMC yaba biopolymer?

Hydroxypropylmethylcellulose (HPMC) ni uburyo bwo guhindura imikorere ya selile, polymer karemano iboneka murukuta rwibimera. Mugihe HPMC ubwayo itari biopolymer kuva ikozwe muburyo bwa chimique, akenshi ifatwa nkigice cya sintetike cyangwa biopolymer yahinduwe.

A. Intangiriro kuri hydroxypropyl methylcellulose:

Hydroxypropyl methylcellulose (HPMC):

Hydroxypropylmethylcellulose (HPMC) ni inkomoko ya selile, polymer y'umurongo ugizwe na glucose. Cellulose nigice cyingenzi cyubaka urukuta rwibimera. HPMC ikorwa muburyo bwo guhindura selile yongeyeho hydroxypropyl na methyl matsinda.

B. Imiterere n'imikorere:

1.Imiterere yimiti:

Imiterere yimiti ya HPMC igizwe na selile yumugongo ya selile irimo hydroxypropyl na methyl. Impamyabumenyi yo gusimbuza (DS) bivuga impuzandengo ya hydroxypropyl na methyl matsinda kuri glucose igice cyumunyururu wa selile. Ihinduka rihindura imiterere yumubiri na chimique ya selile, bivamo urutonde rwamanota ya HPMC hamwe nubwiza butandukanye, solubilité na gel.

2.Imiterere yumubiri:

Gukemura: HPMC ishonga mumazi ikanatanga ibisubizo bisobanutse, bigatuma iba ingirakamaro mubikorwa bitandukanye birimo imiti, ibiryo, nubwubatsi.

Viscosity: Ubukonje bwumuti wa HPMC burashobora kugenzurwa muguhindura urwego rwo gusimbuza nuburemere bwa molekile ya polymer. Uyu mutungo ningirakamaro mubisabwa nkibikoresho bya farumasi nibikoresho byubwubatsi.

3. Imikorere:

Inkoko: HPMC ikoreshwa cyane mubyimbye mubiribwa, imiti, nibicuruzwa byumuntu.

Gukora firime: Irashobora gukora firime kandi irashobora gukoreshwa mugutwikira ibinini bya farumasi na capsules, ndetse no gukora firime kubikorwa bitandukanye.

Kubika Amazi: HPMC izwiho gufata neza amazi, ifasha kunoza imikorere nogutwara ibikoresho byubaka nkibicuruzwa bishingiye kuri sima.

C. Gushyira mu bikorwa HPMC:

1. Ibiyobyabwenge:

Ipitingi ya Tablet: HPMC ikoreshwa mugukora ibinini bya tablet kugirango igenzure ibiyobyabwenge kandi bitezimbere.

Gutanga ibiyobyabwenge mu kanwa: Biocompatibilité hamwe nuburyo bugenzurwa bwa HPMC bituma bikwiranye na sisitemu yo gutanga imiti yo mu kanwa.

Inganda zubaka:

Ibicuruzwa bya Mortar na sima: HPMC ikoreshwa mubikoresho byubwubatsi mugutezimbere amazi, gukora no gufatira hamwe.

3. Inganda zibiribwa:

Thickeners and Stabilisers: HPMC ikoreshwa nkibyimbye kandi bigahindura ibiryo kugirango bitezimbere kandi bihamye.

4. Ibicuruzwa byawe bwite:

Amavuta yo kwisiga: HPMC yinjijwe muburyo bwo kwisiga kugirango ikore firime kandi yibyibushye.

5.Irangi hamwe na Coatings:

Amazi yo mu mazi: Mu nganda zitwikiriye, HPMC ikoreshwa muburyo bwo gufata amazi kugirango itezimbere rheologiya kandi irinde ko pigment itura.

6. Ibidukikije:

Mugihe HPMC ubwayo itari polymer yuzuye ibinyabuzima, inkomoko yayo ya selile ituma ugereranije nibidukikije ugereranije na polimeri yuzuye. HPMC irashobora kwangiza ibinyabuzima mu bihe bimwe na bimwe, kandi ikoreshwa ryayo mu buryo burambye kandi bw’ibinyabuzima ni agace k’ubushakashatsi bukomeje.

Hydroxypropylmethylcellulose (HPMC) ni polymer yimikorere myinshi igizwe na polymer ikomoka kuri selile. Imiterere yihariye itanga agaciro mubikorwa bitandukanye birimo imiti, ubwubatsi, ibiryo, kwita kumuntu no gusiga amarangi. Nubwo atari uburyo bwiza bwa biopolymer, inkomoko ya selile hamwe nubushobozi bwa biodegradation bihuye nibikenewe bigenda byiyongera kubikoresho byinshi birambye mubikorwa bitandukanye. Ubushakashatsi burimo gukorwa bukomeje gushakisha uburyo bwo kuzamura ibidukikije bya HPMC no kwagura imikoreshereze y’ibidukikije.