Hydroxypropyl methylcellulose, 28-30% mikorobe, 7-12% hydroxypropyl

Ibisobanuro "28-30% mikoro" na "7-12% hydroxypropyl" bivuga urwego rwo gusimbuza muriHydroxypropyl Methylcellulose(HPMC). Indangagaciro zerekana urugero polymer yumwimerere ya selulose yahinduwe muburyo bwa chimique hamwe na mikoro ya hydroxypropyl.

1. 28-30% Methoxyl:
   • Ibi byerekana ko, ugereranije, 28-30% byamatsinda ya hydroxyl yumwimerere kuri molekile ya selile yasimbujwe amatsinda ya mikorerexyl. Amatsinda ya Methoxyl (-OCH3) yatangijwe kugirango yongere hydrophobicity ya polymer.
2. 7-12% Hydroxypropyl:
   • Ibi bivuze ko, ugereranije, 7-12% byamatsinda ya hydroxyl yumwimerere kuri molekile ya selile yasimbujwe amatsinda ya hydroxypropyl. Amatsinda ya Hydroxypropyl (-OCH2CHOHCH3) yatangijwe kugirango yongere amazi kandi ahindure indi miterere yumubiri na chimique ya polymer.

Urwego rwo gusimbuza rugira ingaruka kumiterere ya HPMC n'imikorere yayo mubikorwa bitandukanye. Urugero:

• Ubusanzwe metoxyl yibintu byinshi byongera hydrophobicity ya polymer, bigira ingaruka kumyuka yamazi nibindi bintu.
• Ibirungo byinshi bya hydroxypropyl birashobora kuzamura amazi no gukora firime ya HPMC.

Ibi bisobanuro ni ngombwa mu kudoda HPMC kugirango byuzuze ibisabwa mu nganda zitandukanye. Kurugero, muruganda rwa farumasi, guhitamo icyiciro cya HPMC hamwe nimpamyabumenyi yihariye yo gusimbuza bishobora kugira ingaruka kumwirondoro wo gusohora ibiyobyabwenge muburyo bwa tablet. Mu nganda zubaka, zirashobora kugira ingaruka kumazi no gufata neza ibicuruzwa bishingiye kuri sima.

Ababikora bakora amanota atandukanye ya HPMC hamwe nimpamyabumenyi zitandukanye zo gusimbuza kugirango bakemure ibyifuzo bitandukanye bya porogaramu zitandukanye. Iyo ukoresheje HPMC mubisobanuro, nibyingenzi kubashinzwe gusuzuma icyiciro cyihariye cya HPMC gihuza nibintu byifuzwa nibikorwa biranga porogaramu igenewe.