HPMC VS HEC: Itandukaniro 6 Ukeneye Kumenya!

Intangiriro:

Hydroxypropylmethylcellulose (HPMC) na hydroxyethylcellulose (HEC) byombi ni inyongeramusaruro zikoreshwa mu biribwa, amavuta yo kwisiga n’imiti. Ibikomoka kuri selile bifite amahirwe menshi yo gukoreshwa bitewe nuburyo budasanzwe bwo gukemura amazi, gukomera kwinshi, hamwe nubushobozi buhebuje bwo gukora film.

1.Imiterere yimiti:

HPMC ni polymer synthique ikomoka kuri selile. Ikozwe muburyo bwa chimique ihindura selile isanzwe yongeramo oxyde ya propylene na methyl chloride. HEC kandi ni ubwoko bukomoka kuri selile, ariko bukozwe no gukora selile naturel na okiside ya Ethylene hanyuma ikayivura na alkali.

2. Gukemura:

HPMC na HEC byombi birashobora gushonga amazi kandi birashobora gushonga mumazi akonje. Ariko gukemura kwa HEC biri munsi ya HPMC. Ibi bivuze ko HPMC ifite itandukaniro ryiza kandi irashobora gukoreshwa muburyo bworoshye.

3. Viscosity:

HPMC na HEC bifite imiterere itandukanye yubukorikori bitewe nuburyo bwimiti yabyo. HEC ifite uburemere buke bwa molekuline hamwe nuburyo bwimbitse kuruta HPMC, itanga ubwiza bwinshi. Kubwibyo, HEC ikoreshwa cyane mubyimbye muburyo busaba ubukonje bwinshi, mugihe HPMC ikoreshwa muburyo busaba ububobere buke.

4. Igikorwa cyo gukora firime:

HPMC na HEC zombi zifite ubushobozi bwiza bwo gukora film. Ariko HPMC ifite ubushyuhe buke bwo gukora firime, bivuze ko ishobora gukoreshwa mubushyuhe buke. Ibi bituma HPMC ikwiranye no gukoreshwa muburyo busaba ibihe byumye byihuse kandi bifatanye neza.

5. Guhagarara:

HPMC na HEC birahagaze neza mubihe byinshi pH nubushyuhe. Ariko, HEC yunvikana cyane nimpinduka za pH kuruta HPMC. Ibi bivuze ko HEC igomba gukoreshwa mubisobanuro bifite pH ya 5 kugeza 10, mugihe HPMC ishobora gukoreshwa mugari ya pH.

6. Gusaba:

Ibintu bitandukanye biranga HPMC na HEC bituma bibera mubikorwa bitandukanye. HEC isanzwe ikoreshwa nkibikoresho byo kwisiga no kwisiga. Irakoreshwa kandi nka binder na firime ikora firime muburyo bwa tablet. HPMC ikoreshwa nkibibyimbye, stabilisateur, hamwe nogukora firime mubiribwa, ibiyobyabwenge, no kwisiga. Irakoreshwa kandi nka gelling agent mubisabwa bimwe mubiryo.

Mu gusoza:

HPMC na HEC byombi biva muri selile hamwe nibintu byihariye bikwiranye na porogaramu zitandukanye. Gusobanukirwa itandukaniro riri hagati yibi byongeweho byombi birashobora kugufasha guhitamo igikwiye kuri resept yawe. Muri rusange, HPMC na HEC ni inyongeramusaruro zifite umutekano kandi zingirakamaro zitanga inyungu nyinshi mubiribwa, amavuta yo kwisiga n’imiti.