Methylcellulose (MC) nikintu gisanzwe gikoreshwa muburyo bwa chimique synthesis polymer, ether ya selile yahinduwe yabonetse hakoreshejwe methylating selile selile. Bitewe nimiterere yihariye yumubiri nubumashini, ikoreshwa cyane mubwubatsi, ibiryo, ubuvuzi, kwisiga, impapuro no gutwikira.
1. Gutondekanya ukurikije urwego rwo gusimburwa
Urwego rwo gusimbuza (DS) bivuga agaciro kagereranijwe k'amatsinda ya hydroxyl yasimbujwe n'amatsinda ya methyl kuri buri gice cya glucose muri methylcellulose. Hano hari amatsinda 3 ya hydroxyl kuri buri mpeta ya glucose ya molekile ya selile ishobora gusimburwa nitsinda rya methyl. Kubera iyo mpamvu, urugero rwo gusimbuza methylcellulose rushobora gutandukana kuva kuri 0 kugeza kuri 3. Ukurikije urwego rwo gusimbuza, methylcellulose irashobora kugabanywamo ibyiciro bibiri: urwego rwo hejuru rwo gusimburwa nu rwego rwo hasi rwo gusimburwa.
Urwego rwo hejuru rwo gusimbuza methylcellulose (DS> 1.5): Ubu bwoko bwibicuruzwa bufite urwego rwo hejuru rwo gusimbuza methyl, bityo rero ni hydrophobique, ifite imbaraga nke kandi irwanya amazi meza. Bikunze gukoreshwa mubikoresho byubaka, gutwikira nibindi bihe bisaba urwego runaka rwa hydrophobicity.
Urwego rwo hasi rwo gusimbuza methylcellulose (DS <1.5): Bitewe no gusimbuza methyl nkeya, ubu bwoko bwibicuruzwa ni hydrophilique, bufite imbaraga zo gushonga kandi burashobora gushonga mumazi akonje. Methylcellulose isimbuwe cyane ikoreshwa cyane mubikorwa byibiribwa n’imiti nkibyimbye, emulisiferi na stabilisateur.
2. Gutondekanya ukoresheje
Ukurikije ikoreshwa rya methylcellulose mubice bitandukanye, irashobora kugabanywamo ibyiciro bibiri: methylcellulose yinganda nibiribwa na methylcellulose yimiti.
Methylcellulose yinganda: Ahanini ikoreshwa mubwubatsi, gutwika, gukora impapuro, gukora ubukerarugendo nizindi nganda nkibyimbye, bifata, firime yahoze, umukozi ushinzwe gufata amazi, nibindi. kuramba; mu nganda zitwikiriye, methylcellulose irashobora kongera ituze no gutandukana kwimyenda.
Ibiryo na farumasi methylcellulose: Bitewe nuburozi butagira uburozi kandi butagira ingaruka, methylcellulose ikoreshwa nkinyongera mubiribwa nubuvuzi. Mu biryo, methylcellulose ni umubyimba usanzwe hamwe na emulisiferi ushobora guhagarika imiterere yibiribwa no kwirinda gutandukana cyangwa gutandukana; murwego rwa farumasi, methylcellulose irashobora gukoreshwa nkigikonoshwa cya capsule, itwara ibiyobyabwenge, kandi ikaba ifite ninshingano yibiyobyabwenge birekura. Kuribwa kwayo n'umutekano bituma methylcellulose ikundwa cyane muribi bice byombi.
3. Gutondekanya muburyo bwo kwikemurira ibibazo
Methylcellulose igabanijwemo ibyiciro bibiri muburyo bwo gukemuka: ubwoko bwamazi akonje nubwoko bwa solvent soluble.
Amazi akonje ashonga methylcellulose: Ubu bwoko bwa methylcellulose burashobora gushonga mumazi akonje kugirango bibe igisubizo kiboneye, kibonerana nyuma yo guseswa. Bikunze gukoreshwa mubiribwa na farumasi nkibibyimbye cyangwa firime yahoze. Ubushobozi bwubu bwoko bwa methylcellulose bugabanuka hamwe nubushyuhe bwiyongera, ubwo rero iyi mikorere irashobora gukoreshwa mugucunga ubwubatsi iyo ikoreshejwe mubikorwa byubwubatsi.
Organic solvent soluble methylcellulose: Ubu bwoko bwa methylcellulose burashobora gushonga mumashanyarazi kama kandi bukoreshwa kenshi mumarangi, gutwikira hamwe nizindi nganda zisaba itangazamakuru ryicyiciro cya organic. Bitewe nuburyo bwiza bwo gukora firime no kurwanya imiti, birakwiriye gukoreshwa mubihe bikomeye byinganda.
4. Gutondekanya kuburemere bwa molekile (viscosity)
Uburemere bwa molekuline ya methylcellulose bugira ingaruka zikomeye kumiterere yumubiri, cyane cyane imikorere yubusa mubisubizo. Ukurikije uburemere bwa molekile, methylcellulose irashobora kugabanywa mubwoko buke bwubwiza nubwoko bwinshi bwubwiza.
Methylcellulose ya viscosity nkeya: Uburemere bwa molekile ni buto kandi igisubizo cyibisubizo ni gito. Bikunze gukoreshwa mubiribwa, ubuvuzi no kwisiga, cyane cyane muri emulisation, guhagarika no kubyimba. Methylcellulose ifite ubukonje buke irashobora kugumana amazi meza hamwe nuburinganire, kandi irakwiriye mubisabwa bisaba ibisubizo bike-by-ibisubizo.
Methylcellulose-yuzuye cyane: Ifite uburemere bunini bwa molekile kandi ikora igisubizo cyinshi cyane nyuma yo guseswa. Bikunze gukoreshwa mubikoresho byo kubaka, gutwikira no gufatira mu nganda. Methylcellulose ifite ubukana bwinshi irashobora kongera imbaraga zumukanishi, kwambara no guhangana nigisubizo, bityo ikoreshwa cyane mubikoresho bisaba imbaraga nyinshi kandi birwanya kwambara cyane.
5. Gutondekanya ukurikije urwego rwo guhindura imiti
Methylcellulose ni imiti ikomoka kuri selile. Ukurikije uburyo bwo guhindura no kurwego, birashobora kugabanywamo methyl selile imwe hamwe na selile yahinduwe.
Methyl selile imwe imwe: bivuga ether ya selile isimburwa na methyl gusa. Ubu bwoko bwibicuruzwa bifite imiterere ihamye yumubiri nubumara, kandi gukomera kwayo, kubyimba no gukora firime nibyiza.
Guhindura selile yahinduwe: Usibye methylation, irakoreshwa kandi muburyo bwa chimique, nka hydroxypropylation, Ethylation, nibindi, kugirango ikore ibicuruzwa byahinduwe. Kurugero, hydroxypropyl methylcellulose (HPMC) na carboxymethyl selulose (CMC). Izi selile zahinduwe mubisanzwe zifite amazi meza, guhangana nubushyuhe no gutuza, kandi birashobora guhuza ninganda nyinshi zikenewe mu nganda.
6. Gutondekanya ninganda zikoreshwa
Ikoreshwa ryinshi rya methylcellulose ryemerera gushyirwa mubikorwa ukurikije imiterere yabyo mubikorwa bitandukanye.
Inganda zubaka methylcellulose: Ahanini ikoreshwa mubikoresho bishingiye kuri sima hamwe na gypsumu nkibikoresho byo kubika amazi no kubyimba. Irashobora kunoza imikorere yibikoresho byubaka, ikabuza gutakaza amazi hakiri kare, kandi ikongerera imbaraga imashini zikoreshwa mubicuruzwa byarangiye.
Inganda zikora ibiribwa methylcellulose: Nka emulifisiyeri, ikabyimbye kandi ikomeza gutunganya ibiryo. Irashobora gukumira gutakaza amazi, kunoza uburyohe nimiterere yibyo kurya, no kongera ubuzima bwibiryo.
Uruganda rwa farumasi methylcellulose: Nkibikoresho bya tablet cyangwa ibikoresho birekura-biyobyabwenge. Methylcellulose irashobora kandi gukoreshwa mugutegura imiti yigifu nkigitwara ibiyobyabwenge byizewe kandi byiza.
Inganda zo kwisiga methylcellulose: Mubicuruzwa byita ku ruhu no kwisiga, methylcellulose ikoreshwa nkibyimbye, emulisiferi na moisturizer kugirango ifashe ibicuruzwa gukora ibintu byoroshye kandi byoroshye mugihe byongerera imbaraga ubushuhe.
Muncamake, hariho inzira nyinshi zo gutondekanya methylcellulose, ishobora gutondekwa ukurikije imiterere yimiterere yimiti, cyangwa ukurikije imirima yabyo hamwe nuburyo bwo gukemura. Ubu buryo butandukanye bwo gutondekanya budufasha kumva neza ibiranga n'imikorere ya methylcellulose, kandi bikanatanga ishingiro ryuburyo bwo kubishyira mubikorwa bitandukanye.
Igihe cyo kohereza: Ukwakira-23-2024