Hydroxypropyl selulose (HPC) ni polymer ikoreshwa cyane mu nganda zitandukanye, harimo imiti, amavuta yo kwisiga, n'ibiribwa.Kimwe na polymers nyinshi, ubushyuhe bwumuriro nubushyuhe bwabyo biterwa nibintu byinshi nkuburemere bwa molekile, urugero rwo gusimburwa, kuba hari inyongeramusaruro, nuburyo bwo gutunganya.Ariko, nzaguha incamake yibintu bigira ingaruka kumyuka yubushyuhe ya HPC, ubushyuhe bwayo busanzwe, hamwe na bimwe mubisabwa.
1. Imiterere yimiti ya HPC:
Hydroxypropyl selulose ni inkomoko ya selile yabonetse mu kuvura selile hamwe na okiside ya propylene.Ihindurwa ryimiti ritanga solubile nibindi bintu byifuzwa kuri selile, bigatuma bigira akamaro mubikorwa bitandukanye.
2. Ibintu bigira ingaruka kumyuka yubushyuhe:
a.Uburemere bwa molekuline: Uburemere buke bwa molekile HPC ikunda kugira ubushyuhe bwinshi bitewe nimbaraga zikomeye za intermolecular.
b.Impamyabumenyi yo gusimburana (DS): Ingano yo gusimbuza hydroxypropyl igira ingaruka kumyuka ya HPC.DS yo hejuru irashobora gutuma ubushyuhe bugabanuka bitewe nubwiyongere bukabije bwumuriro.
c.Kuba hari inyongeramusaruro: Inyongeramusaruro zimwe zishobora kongera ubushyuhe bwumuriro wa HPC mukora nka stabilisateur cyangwa antioxydants, mugihe izindi zishobora kwihuta.
d.Uburyo bwo gutunganya: Ibihe HPC itunganyirizwamo, nkubushyuhe, umuvuduko, no guhura nikirere cyangwa ibindi bidukikije, birashobora kugira ingaruka kumyuka yubushyuhe.
3. Uburyo bwo Kwangiza Ubushyuhe:
Kwangirika kwubushyuhe bwa HPC mubisanzwe birimo gucamo glycosideque mumigongo ya selile no gutandukanya imiyoboro ya ether yatangijwe no gusimbuza hydroxypropyl.Iyi nzira irashobora gutuma habaho ibicuruzwa bihindagurika nkamazi, dioxyde de carbone, na hydrocarbone zitandukanye.
4. Ubusanzwe Ubushyuhe bwo Kugabanuka:
Ubushyuhe bwa HPC burashobora gutandukana cyane bitewe nibintu byavuzwe haruguru.Muri rusange, ubushyuhe bwa HPC butangira hafi 200 ° C kandi burashobora gukomeza kugera ku bushyuhe bugera kuri 300-350 ° C.Nyamara, uru rutonde rushobora guhinduka bitewe nuburyo bwihariye buranga icyitegererezo cya HPC nuburyo bugaragarira.
5. Gusaba HPC:
Hydroxypropyl selulose isanga ikoreshwa mubikorwa bitandukanye:
a.Imiti ya farumasi: Ikoreshwa nkibyimbye, binder, firime yahoze, kandi igenzurwa-kurekura imiti mu miti nka tableti, capsules, hamwe nimyiteguro yibanze.
b.Amavuta yo kwisiga: HPC ikoreshwa mubintu byo kwisiga hamwe nibicuruzwa byumuntu ku giti cye nkumubyimba, stabilisateur, na firime byahoze mubicuruzwa nka amavuta yo kwisiga, amavuta, hamwe no gutunganya umusatsi.
c.Inganda z’ibiribwa: Mu nganda z’ibiribwa, HPC ikora nk'ibyimbye, stabilisateur, na emulisiferi mu bicuruzwa nka sosi, isupu, hamwe n’ubutayu.
d.Inganda zikoreshwa mu nganda: HPC ikoreshwa kandi mubikorwa bitandukanye byinganda nka wino, impuzu, hamwe nudusumari kubera imiterere ya firime na rheologiya.
ubushyuhe bwo gutakaza ubushyuhe bwa hydroxypropyl selulose buratandukana bitewe nuburemere nkuburemere bwa molekile, urugero rwo gusimburwa, kuba hari inyongeramusaruro, nuburyo bwo gutunganya.Mugihe iyangirika ryayo ritangira hafi 200 ° C, irashobora gukomeza kugera ku bushyuhe bwa 300-350 ° C.Gusobanukirwa nibintu bigira ingaruka kumyuka yubushyuhe ningirakamaro mugutezimbere imikorere yayo mubikorwa bitandukanye mubikorwa bitandukanye.
Igihe cyo kohereza: Werurwe-26-2024