Hydroxypropyl methylcellulose (HPMC) na hypromellose mubyukuri nibintu bimwe, kandi amagambo akoreshwa muburyo bumwe. Aya ni amazina atoroshye kubwoko busanzwe bwa selile-ishingiye kuri polymers ifite uburyo bwinshi bwo gukoresha mubikorwa bitandukanye birimo imiti, ibiryo na cosmetike.
1.Imiterere yimiterere nibigize:
Hydroxypropylmethylcellulose (HPMC) ni uburyo bwo guhindura imikorere ya selile, polymer karemano iboneka murukuta rwibimera. Imiterere yimiti ya HPMC iboneka mugutangiza hydroxypropyl na methyl matsinda ashingiye kuri selile. Itsinda rya hydroxypropyl rituma selile irushaho gushonga mumazi, kandi methyl itsinda ryongera ituze kandi rigabanya reaction.
2. Uburyo bwo gukora:
Umusaruro wa hydroxypropyl methylcellulose urimo kuvura selile hamwe na oxyde ya propylene kugirango utangire amatsinda ya hydroxypropyl hanyuma hamwe na methyl chloride kugirango wongere amatsinda ya methyl. Urwego rwo gusimbuza (DS) rwa hydroxypropyl na methyl rushobora guhinduka mugihe cyo gukora, bikavamo amanota atandukanye ya HPMC hamwe nibintu bitandukanye.
3. Imiterere yumubiri:
HPMC ni ifu yera kugeza gato-ifu yera, idafite impumuro nziza kandi itaryoshye. Imiterere yumubiri, nka viscosity and solubible, biterwa nurwego rwo gusimbuza nuburemere bwa molekile ya polymer. Mubihe bisanzwe, byoroshye gushonga mumazi, bigakora igisubizo kiboneye kandi kitagira ibara.
4. Intego z'ubuvuzi:
Imwe mubikorwa nyamukuru bya HPMC ni muruganda rwa farumasi. Ikoreshwa cyane nkibikoresho bya farumasi kandi bigira uruhare runini mugutegura imiti. HPMC ikunze kuboneka muburyo bukomeye bwa dosiye nkibinini, capsules, n'ibinini. Ikora nk'umuntu uhuza, udahuzagurika, kandi agenzurwa n'umukozi wo kurekura, bigira uruhare mu gutuza muri rusange no kubaho kwa bioavailable.
5. Uruhare mugutegura kurekurwa:
Ubushobozi bwa HPMC bwo gukora geles mubisubizo byamazi bituma igira agaciro mumiti igenzurwa-irekura. Muguhindura imiterere yimiterere nubwiza bwa gel, abahanga mubya farumasi barashobora kugenzura igipimo cyo kurekura ibintu bikora, bityo bakagera kubikorwa byibiyobyabwenge kandi biramba.
6. Gusaba mu nganda zibiribwa:
Mu nganda zibiribwa, HPMC ikoreshwa nkibyimbye, stabilisateur na emulifier. Itezimbere ibiryo bitandukanye, harimo isosi, isupu nibikomoka ku mata. Byongeye kandi, HPMC ikoreshwa muguteka kutagira gluten kugirango yongere imiterere nubushuhe bwibicuruzwa bitarimo gluten.
7. Ibikoresho byo kubaka no kubaka:
HPMC ikoreshwa mu nganda zubaka mu bicuruzwa nk'ibiti bifata tile, plaque ishingiye kuri sima n'ibikoresho bishingiye kuri gypsumu. Itezimbere uburyo bwo gutunganya, kubika amazi hamwe nibiranga ibicuruzwa.
8. Amavuta yo kwisiga n'ibicuruzwa byita ku muntu:
Hypromellose nayo ni ibintu bisanzwe mubisiga no kwisiga. Ikoreshwa muri cream, amavuta yo kwisiga hamwe na shampo kubera kubyimbye no gutuza. Byongeye kandi, ifasha kunoza imiterere rusange no kumva ibicuruzwa.
9. Gufata amashusho muri farumasi:
HPMC ikoreshwa cyane mu nganda zimiti mugutunganya ibinini bya tableti. Ibinini bisize firime bitanga isura nziza, guhisha uburyohe no kurinda ibidukikije. Filime ya HPMC itanga igifuniko cyoroshye kandi kimwe, kizamura ubwiza bwibicuruzwa byibiyobyabwenge.
13. Umwanzuro:
Hydroxypropyl methylcellulose (HPMC) na hypromellose bivuga polimeri imwe ishingiye kuri selile ifite uburyo butandukanye mubikoresho bya farumasi, ibiryo, amavuta yo kwisiga, nubwubatsi. Imiterere yihariye, nko gukemuka, gutuza no kubora ibinyabuzima, bigira uruhare mugukoresha kwinshi. Ubwinshi bwa HPMC mu nganda zitandukanye bugaragaza akamaro kayo nkibikoresho byinshi, kandi bikomeza regushakisha niterambere birashobora kuvumbura izindi porogaramu mugihe kizaza.
Iyi ncamake yuzuye igamije gutanga ibisobanuro birambuye kuri hydroxypropyl methylcellulose na hypromellose, gusobanura akamaro kabo mubice bitandukanye, no gusobanura uruhare rwabo mugukora ibicuruzwa byinshi nibisobanuro.
Igihe cyo kohereza: Ukuboza-21-2023