Ikoreshwa rya Ethers ya Cellulose munganda zimiti nibiribwa
Ether ya selile ikoreshwa cyane mubikorwa bya farumasi nibiribwa kubera imiterere yihariye nibisabwa bitandukanye. Hano haribintu bisanzwe bikoreshwa muri selile ya ether muri iyi mirenge:
- Inganda zimiti:
a. Gukora Tablet: Ethers ya selile nka hydroxypropyl methylcellulose (HPMC) na carboxymethyl selulose (CMC) ikoreshwa cyane nka binders, disintegrants, hamwe nubushakashatsi bugenzurwa-mububiko. Zitanga ibintu byiza cyane bihuza, byorohereza guhunika ifu mubinini, mugihe binateza imbere gusenyuka vuba no gusesa ibinini mumitsi ya gastrointestinal. Ether ya selile ifasha kunoza itangwa ryibiyobyabwenge na bioavailable, kwemeza ibiyobyabwenge kimwe no kwinjiza.
b. Ibyingenzi byingenzi: Ethers ya selile ikoreshwa muburyo bukomeye nka cream, geles, amavuta, n'amavuta yo kwisiga nkibibyimbye, stabilisateur, na emulisiferi. Zongera ubwiza, gukwirakwira, hamwe nuburyo bwibicuruzwa byingenzi, bigufasha gukoreshwa neza no gutwikira uruhu neza. Ether ya selile nayo itanga ibintu bitanga amazi kandi bigakora firime, bigatera ibiyobyabwenge kwinjira no kwinjizwa muruhu.
c. Sisitemu Zirambye-Kurekura: Ethers ya selile yinjizwa muburyo burambye-burekura kugirango igenzure kinetics irekura ibiyobyabwenge kandi ikore ibikorwa byibiyobyabwenge. Bakora matrix cyangwa gel imiterere idindiza irekurwa ryibiyobyabwenge, bikavamo irekurwa rihoraho kandi rigenzurwa mugihe kinini. Ibi bituma kugabanya inshuro nyinshi, kunoza kubahiriza abarwayi, no kuvura neza.
d. Imyiteguro y'amaso: Muburyo bw'amaso nk'ibitonyanga by'amaso, geles, n'amavuta, ether ya selile ikora nk'imitsi itera imbaraga, amavuta yo kwisiga, hamwe na mucoadhesive. Bongera igihe cyo gutura kwa formulaire hejuru ya ocular, bitezimbere ibiyobyabwenge bioavailability hamwe nubuvuzi bwiza. Ethers ya selile nayo yongerera ihumure no kwihanganira ibicuruzwa byamaso, bikagabanya uburakari no kutoroherwa na ocular.
- Inganda zikora ibiribwa:
a. Thickeners and Stabilisers: Ethers ya selile ikoreshwa cyane nkibibyimbye hamwe na stabilisateur mubicuruzwa bitandukanye byibiribwa, birimo isosi, imyambarire, isupu, desert, nibikomoka ku mata. Zitanga ubwiza, ubwiza, hamwe numunwa wibiryo byokurya, bikongerera ibyiyumvo byabo no kwakira abaguzi. Ether ya selile itezimbere ituze, ihamye, nigaragara ryibicuruzwa byibiribwa, birinda gutandukanya ibyiciro, synereze, cyangwa ubutayu.
b. Gusimbuza ibinure: Ethers ya selile ikoreshwa nk'abasimbuza ibinure mu bicuruzwa birimo amavuta make cyangwa yagabanijwe-karori kugirango bigane imiterere n'amavuta yo mu kanwa. Bakora nkibintu byinshi hamwe na emulisiferi, batanga amavuta nubutunzi mubiribwa batongeyeho karori cyangwa cholesterol. Ethers ya selile ifasha kugabanya ibinure byibicuruzwa byibiribwa mugihe bikomeza uburyohe, imiterere, hamwe nubwumvikane buke.
c. Emulisiferi na Stabilisateur ya Foam: Ethers ya selile ikora nka emulisiferi na stabilisateur ya furo muri emulisiyo yibiribwa, ifuro, nibicuruzwa byuka. Biteza imbere gushiraho no gutuza kwa emulisiyo, birinda gutandukanya icyiciro na cream. Ethers ya selile nayo yongerera imbaraga nubunini bwamafuro, igateza imbere imiterere yumunwa wibiryo byuka bihumeka nka pompe, mousses, hamwe na cream.
d. Guteka kwa Gluten: Ethers ya selile ikoreshwa nkibibyimba kandi bihuza muburyo bwo guteka butarimo gluten kugirango bitezimbere imiterere, imiterere, hamwe nubushuhe bwibicuruzwa bitetse. Barigana imiterere ya viscoelastic ya gluten, itanga ubworoherane nuburyo bwimigati mumigati idafite gluten, keke, hamwe nudutsima. Ether ya selile ifasha gutsinda imbogamizi zijyanye no guteka gluten, bikavamo ibicuruzwa byiza kandi byiza biryoheye.
selile ya selile ifite uruhare runini mubikorwa bya farumasi n’ibiribwa, bigira uruhare mu kunoza imikorere y’ibicuruzwa, ituze, no guhaza abaguzi. Guhindura byinshi, umutekano, no kwemezwa nubuyobozi bituma bongerwaho agaciro muburyo butandukanye bwo gusaba, gushyigikira udushya no guteza imbere ibicuruzwa muriyi nzego.
Igihe cyo kohereza: Gashyantare-11-2024