Ikoreshwa rya HPMC mu nganda zimiti

Hydroxypropyl methylcellulose (HPMC), izwi kandi nka hypromellose, ikoreshwa cyane mu nganda zimiti kubera imiterere yayo itandukanye. Hano hari bimwe mubisanzwe HPMC muri farumasi:

1. Ibikoresho bya Tablet: HPMC isanzwe ikoreshwa nkumuhuza mugutegura ibinini kugirango itange ubumwe kandi itezimbere ubukana bwa tablet. Ifasha gufata ifu yibikoresho hamwe mugihe cyo kwikuramo, bikavamo ibinini bifite imbaraga hamwe nubukanishi.
2. Umukozi wa Firime: HPMC ikoreshwa nkibikoresho byo gutwika firime kugirango itange uburinzi na / cyangwa ubwiza bwiza kuri tableti na capsules. Ipitingi ya firime itezimbere isura, uburyohe bwa mask, hamwe nuburyo bwimiti ya farumasi. Byongeye kandi, irashobora kugenzura imiti irekura ibiyobyabwenge, ikarinda ibiyobyabwenge ubuhehere, kandi ikoroha kumira.
3. Matrix Yahoze: HPMC ikoreshwa nka matrix yahoze mugucungwa-kurekura no gukomeza-kurekura ibinini bya tablet. Ikora geli ya hydrata, igenzura ikwirakwizwa ryibiyobyabwenge bivuye kumiterere ya dosiye, biganisha kumiti igihe kirekire kandi bikagira ingaruka nziza zo kuvura.
4. Gutandukana: Mubisobanuro bimwe, HPMC irashobora gukora nkigisebanya, igateza imbere gusenyuka byihuse no gukwirakwiza ibinini cyangwa capsules mu nzira ya gastrointestinal. Ibi byoroshya gusesa ibiyobyabwenge no kubyakira, byemeza neza bioavailable.
5. Guhindura Viscosity: HPMC ikoreshwa nkibihindura viscosity mumazi na kimwe cya kabiri gikomeye nko guhagarikwa, emulisiyo, geles, namavuta. Itanga igenzura rya rheologiya, itezimbere ihagarikwa ryihagarikwa, kandi ikongerera ikwirakwizwa no gufatira ibyemezo byingenzi.
6. Stabilisateur na Emulsifier: HPMC ikoreshwa nka stabilisateur na emulisiferi mu mazi y’amazi kugirango birinde gutandukanya ibice, kunoza ihagarikwa, no kuzamura uburinganire bwibicuruzwa. Bikunze gukoreshwa muburyo bwo guhagarika umunwa, sirupe, na emulisiyo.
7. Umubyimba: HPMC ikoreshwa nkigikoresho cyo kubyimba muburyo butandukanye bwa farumasi kugirango yongere ububobere kandi itange imiterere ya rheologiya. Itezimbere ubwuzuzanye nuburyo buhoraho bwimyiteguro yibanze nka cream, amavuta yo kwisiga, hamwe na geles, byongera ubwiyongere bwabyo hamwe no kumva uruhu.
8. Opacifier: HPMC irashobora gukoreshwa nkumukozi uhumeka muburyo bumwe kugirango utange ububobere cyangwa kugenzura. Uyu mutungo ni ingirakamaro cyane muburyo bwo kuvura amaso, aho opacite ishobora kunoza neza ibicuruzwa mugihe cyubuyobozi.
9. Imodoka yo gutanga ibiyobyabwenge: HPMC ikoreshwa nkikinyabiziga cyangwa umutwara muri sisitemu yo gutanga ibiyobyabwenge nka microsperes, nanoparticles, na hydrogels. Irashobora gukwirakwiza ibiyobyabwenge, kugenzura ibiyobyabwenge bisohora, no kongera ibiyobyabwenge, bitanga ibiyobyabwenge bigamije kandi bigenzurwa.

HPMC ni imiti itandukanye ikoreshwa na farumasi hamwe nibisabwa byinshi, harimo guhuza ibinini, guhuza firime, kugenzura-gusohora matrix, gusenyuka, guhindura viscosity, stabilisation, emulisation, kubyimba, guhumeka, no gushyiraho uburyo bwo gutanga ibiyobyabwenge. Imikoreshereze yacyo igira uruhare mu iterambere ry’ibicuruzwa bikoreshwa mu bya farumasi bifite umutekano, bikora neza, kandi byorohereza abarwayi.